PDF Ebook Human Molecular Genetics 2, by Tom Strachan, Andrew P. Read
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Human Molecular Genetics 2, by Tom Strachan, Andrew P. Read
PDF Ebook Human Molecular Genetics 2, by Tom Strachan, Andrew P. Read
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Human Molecular Genetics 2 Tom Strachan & Andrew P. Read "truly a Rolls Royce amongst textbooks" — Molecular Medicine Today "the best text to introduce students and scientists to the molecular aspects of human genetics" — Trends in Genetics "a beautifully crafted book" — Journal of Medical Genetics "addresses the gap between introductory textbooks and the primary literature. There’s no other textbook quite like it." — Nature Now extensively rewritten and updated, HMG2 guides students and researchers through the very latest developments in the most rapidly changing area of life science. The highly regarded structure of the bestselling first edition is retained, but a wealth of new data and features have been added to aid understanding of the principles of human molecular genetics:
- new material on cell types and the cell cycle, signal transduction, DNA mutation repair, and comparative genomics and evolution
- new material on recent advances in the study of gene expression and function, including the use of DNA microarrays
- the latest Genome Project data including an assessment of the impact of complete genome sequences and new approaches in functional genomics
- expanded coverage of common disease susceptibility
- new section on how best to obtain the latest data from web-based resources
- a range of new figures, with many more in full color
- the early use of hierarchical figures and flow charts to introduce principles described fully in later chapters
- new two-column layout to improve clarity further
- references systematically updated
- Sales Rank: #2255087 in Books
- Published on: 1999-12-15
- Format: International Edition
- Original language: English
- Number of items: 1
- Dimensions: 10.91" h x .94" w x 8.29" l, .0 pounds
- Binding: Paperback
- 576 pages
Review
"Provides introductory material on DNA and chromosomes...describes principles and applications of cloning and molecular hybridization...presents a guide to...the human genome and human genes...examines mapping of the human genome, study of genetic diseases, and dissection and manipulation of genes." (SciTech Book News Vol. 25, No. 2 June 2001)
Most helpful customer reviews
39 of 42 people found the following review helpful.
The book to read for an in-depth background
By Dr. Lee D. Carlson
This book is a very complete overview of molecular biology as applied to human genetics. As someone interested in bioinformatics and computational biology, I read it to get a background in the biology/genetics behind these fields. That being said, I was glad I made the choice of this book as the authors do a fine job of explaining the relevant concepts and biological processes in genetics. In the light of the recent draft of the human genome, this edition of the book is especially timely. That being said, there is a lot of material covered, and to digest all of the terms and processes outlined takes a fair amount of time. The discussion on functional genomics and the post-genome sequencing era was particularly interesting. More could be said on gene sequencing validation as it applies to gene therapies and drug discovery. The most fascinating chapter was the one on genetic manipulation of animals as this is where genetic engineering has had its successful proving ground. Even though this is a science text, a discussion on the ethics of human genetic engineering would be appropriate, given some of the current attitudes about it. My opinion is that these technologies should move ahead with diligence; humankind cannot afford not to do so.
I would highly recommend this book to those who have the time to read through it, as it offers the necessary concepts needed to understand this fascinating area.
28 of 30 people found the following review helpful.
Excellent for the working student!
By Vince
Being a graduate student in human genetics I was looking long and hard for a comprehensive text on how and why experiment are done in the lab, and the scientific basis for these experiments. This book is the closest one I have seen that accomplishes all these goals. It is a little light on the theoretical side of genetics (e.g. Mendelian etc); however, there are many other texts out there that can substitute for this flaw, but only a few that do what this one does. I recommend this book for students who are familiar with genetics but need to understand the practical side to it.
5 of 26 people found the following review helpful.
a good book, but...
By Alessio D'Ascenzo
This book is enough simple. Chapters regarding the POSITIONAL CLONING, the HYBRIDIZATION, the IMPRINTING and the GENETICAL MAPPAGE are really clear and they represent a big aid for students in the comprehension of these procedures which could be very difficult. But... chapters about GENETICAL DISEAES are too much treated than chapters regarding FORMAL GENETICS, moreover FISICAL MAPPAGE chapter is too detailled in pratical explanation, while the real mappege's concept is not focalized.To conclude a good book, but ... cheers ALESSIO & FEDERICO
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